As an interdisciplinary research institute of the ETH Domain, Empa – the Swiss Federal Laboratories for Materials Science and Technology – conducts cutting-edge materials and technology research. The Advanced Fibers lab in St.Gallen mainly focuses on the modification of flexible materials, also using plasma technologies. Controlled surface modification at the nanoscale is performed by etching, cleaning, plasma polymerization, and (co-)sputtering processes. Our knowledge extends to the successful transfer of such plasma processes to industry supported by R2R pilot-plant reactors both for web and fiber coating as well as simulation tools including production cost models.